Terrell Davis, 27, was reportedly taking shopping to his grandmother when he was fatally stabbed in Brixton Hill.
Tyrece Fuller, 21, appeared via videolink at Bromley Magistrates court on Monday accused of murder.
Judge Vanessa Lloyd sent the case to the Old Bailey where a first hearing is due to take place on Wednesday.
Fuller, of Tavy Close, Lambeth, is charged with one count of murder and one count of possessing a knife. He has been remanded in custody until his next appearance.
Paramedics and air ambulance staff tried to save Mr Davis on the evening of November 22 in Ramillies Close.
British-born rapper 21 Savage, whose real name is She’yaa Bin Abraham-Joseph, paid tribute to his brother by posting a picture of the pair together on Instagram.
The performer wrote: “Can’t believe somebody took you baby bro I know I took my anger out on you I wish I could take that s*** back.”
Source: Evening Standard Business News